What is Feces Canine Parvovirus Pathogen？
Parvovirus can occur throughout the year. It is an infectious disease for dogs with a very high fatality rate in China. There are clinically two types of hemorrhagic enteritis and non-suppurative myocarditis.
Dogs of various ages, genders and breeds are susceptible, mostly in puppies of 2-6 months of age. Purebred dogs are the most infectious, especially newborn puppies, which sometimes show non-suppurative myocarditis and die suddenly and have littermate outbreaks. The characteristics of the source of infection-infected dogs and poisoned dogs, can be detoxified outside 7-14 days after infection, through urine, feces, saliva or vomit, it is very easy to cause food, drinking water and utensils pollution. There is evidence that humans, flies and cockroaches can become mechanical carriers of CPV.
Enteritis type: the incubation period of natural infection is 7-14 days, and artificial infection is 3-4 days. At the first 48 hours of illness, the sick dog was depressed, anorexia, fever (40-41°C) and vomiting. The vomit was mostly food, colorless or light yellow mucus, or mixed with a small amount of bloodshot eyes. After 6-12 hours, diarrhea began. At the beginning of the disease, the stool was yellow or grayish-yellow, mixed with a large amount of white mucus and mucous membrane. In the middle stage, the stool was like coal tar, followed by tomato juice, with a special fishy smell. Rapid dehydration, sunken eyeballs, poor skin elasticity, protruding ribs, no food, fresh water, vomiting after drinking. Less blood in the stool indicates a milder illness and a greater possibility of recovery. Within a few days of vomiting and diarrhea, gastric acid poured into the nasal cavity, causing mucus rhinorrhea.
Myocarditis: It is more common in 28-42-day-old puppies, often without aura, or only mild diarrhea, followed by sudden weakness, dyspnea, fast and weak pulse, bleeding on cardiac auscultation, murmurs, pathological changes in electrocardiogram, short Death within time.
Enteritis: All dogs who died naturally were extremely dehydrated, disappeared, curled up in the abdomen, sunken eyeballs, and pale mucous membranes. **There are loose stools with blood around the **, or bleeding stools from **. Gastric fundus mucosa congestion and bleeding, small intestinal subserosa congestion and bleeding, dark red, the intestine is filled with a lot of smelly and beige content of sorghum, and the intestinal lymph nodes are swollen. Hepatomegaly, hard, splenomegaly, hard. The kidney is enlarged, and the boundary between the cortex and the medulla is unclear.
Myocarditis: pulmonary edema, local congestion, hemorrhage, mottled, dilated heart, relaxation of the left atrium, non-purulent necrosis of the myocardium and endocardium, severe damage to myocardial fibers, and hemorrhagic markings.
Symptomatic treatment: vomiting-Aimol is preferred, atropine if necessary, metoclopramide (do not use when intestinal bleeding) Vb6 and LBQ
Antidiarrheal-tannin protein, Smecta enema.
Hemostasis-hemostatic sensitivity, epinephrine, Anluoxue, Batroxobin.
2. Supportive therapy: maintain heart function, adjust acid-base balance, and restore body condition as soon as possible.
Infusion: basic solution, potassium supplement (0.1-0.2g/kg) calcium supplement (1-2mg/kg) sodium bicarbonate (5% sodium bicarbonate solution, 5ml/KG, 2 times diluted with 5 sugar or 10%) Sugar dilution).
3. Specific therapy: antibiotics + hyperimmune serum (single gram, interferon, immunoglobulin) and other biological agents.
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